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严重了
Relationship Between Urine Bisphenol-A Level and Declining Male Sexual Function
Journal of Andrology, Vol. 31, No. 5, September/October 2010
Abstract
The adverse effect of bisphenol-A (BPA) on the male reproductive system observed in animal studies has not been well examined in human populations. BPA is potentially a serious public health problem because of its widely detected presence in the human body. This study was conducted among 427 male workers in regions where high levels of BPA exposure existed. All participants provided urine samples, which were tested for BPA concentration using high-performance liquid chromatography. Male sexual dysfunction was ascertained using standard male sexual function inventories. Male sexual dysfunction was measured in 4 domains using 7 indices. After controlling for potential confounders using linear regression, increasing urine BPA level was associated with worsening male sexual function on a continuous scale. All 7 indices demonstrated this negative linear correlation. Increasing urine BPA level was associated with decreased sexual desire (P < .001), more difficulty having an erection (P < .001), lower ejaculation strength (P < .001), and lower level of overall satisfaction with sex life (P < .01). A similar negative correlation was also observed among participants exposed to BPA from only environmental sources (no occupational exposure to BPA), although the estimates in this group were less stable because of a smaller sample size. Our results reveal a correlation between a biological measure of urine BPA level and declining male sexual function. This finding may enhance the understanding of the BPA effect in human populations, and may have important public health implications given the widespread human exposure to BPA.
研究者认为,男子性功能衰退与尿中双酚A含量增加有关。
研究人员说,男人性欲减少、勃起困难、射精力度减弱和整体性生活满足感降低,都与尿中双酚A含量增加有关系。这项历经五年的研究,跟踪调查了中国工厂427名工人,对采用和未采用双酚A生产企业的工人进行了比较。 |
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